Technology

The WaferiX™ technology consists of a small wafer prepared by proprietary formulation using the freeze drying process. The wafer is intended to be placed under the tongue, which subsequently dissolves within one minute, releasing the active compounds for rapid absorption in a time sensitive manner. The wafer administration is reported to be tolerable with no after-taste, leaving behind no residue or grittiness under the tongue hence preventing the urge to swallow.

The WaferiX™ technology provides a simple drug carrier matrix with millions of tiny amorphous holes to house (encapsulate) the active drug molecules in a cost effective manner of delivering drugs which otherwise cannot be administered orally due to their poor oral absorption and/or extensive loss to the first pass hepatic metabolism. The only way to administer these drugs is by intravenous administration but sometimes IV route may be impractical (e.g. in traumatic conditions like severe burns). There is also the issue of phobia to injections especially in children and some elderly in which case, a sublingual oral delivery of a pharmaceutical drug is more desirable. For health care workers, it will help prevent needle-stick injuries in compliance to Occupation Safety and Health legislations. The rapid and superior absorption characteristics provide higher bioavailability and a potential to lower the administered dose and reduce the concurrent side effects. These benefits allow for potential application of WaferiX™ in conditions where instantaneous therapeutic effect is desired, like acute or breakthrough pain as well as male erectile dysfunction.

WaferiX™ is a multiple platform drug carrier technology that has been used to develop the world's first sublingual ketamine oral wafer and has been applied to other pharmaceutical drugs like fentanyl and sildenafil citrate. Our technology is easily adaptable to a vast number of other FDA approved drugs that require a faster delivery or reduction in the loss of drugs due to hepatic and gastrointestinal metabolism, hence improving the bioavailability of drugs.

Contact us

iX Biopharma Ltd

1 Kim Seng Promenade
#14-01 Great World City East Tower
Singapore 237994
T: +65 6235 2270
F: +65 6235 2170
E: info@ixbiopharma.com